m-Chloroperbenzoic acid → HCID 69028066, compound

HRID 1594427Notes

Reaction equation

HRID 1594427 reaction equation
[CH2:1]([CH:3]1[CH2:8][CH2:7][CH2:6][CH:5]([C:9]2[S:13][N:12]=[C:11](SC)[N:10]=2)[CH2:4]1)[CH3:2].Cl[C:17]1C=C(C=CC=1)C(OO)=O.[S:27]([O-:30])(O)=[O:28].[Na+]>C(Cl)(Cl)Cl>[CH3:17][S:27]([C:11]1[N:10]=[C:9]([CH:5]2[CH2:6][CH2:7][CH2:8][CH:3]([CH2:1][CH3:2])[CH2:4]2)[S:13][N:12]=1)(=[O:30])=[O:28]

Participants

5

Reactant 3

HCID 70297m-Chloroperbenzoic acidHCID 23665763Sodium BisulfiteHCID 58610416HCID 58610416, compound

Product 1

HCID 69028066HCID 69028066, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

320 mg of 5-(3-ethylcyclohexyl)-3-methylthio-1,2,4-thiadiazole was dissolved in 2.5 ml of chloroform, 738 mg of 3-chloroperoxybenzoic acid (content>65%) was added thereto taking for 20 minutes, and the reaction mixture was stirred for 20 minutes at room temperature. Then, the reaction mixture was added to saturated sodium hydrogensulfite aqueous solution, and separated. The organic layer was washed with sodium hydrogencarbonate aqueous solution, dried over anhydrous sodium sulfate, concentrated to give 380 mg of 3-methylsulfonyl-5-(3-ethylcyclohexyl)-1,2,4-thiadiazole.

Workup

  1. customseparated
  2. washThe organic layer was washed with sodium hydrogencarbonate aqueous solution
  3. dry with materialdried over anhydrous sodium sulfate
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-a5b6024d3cf1480d861c2dcc76c5ded6
Source dataset
uspto-grants-2007_11
Patent number
US07301032B2

Reaction notes

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