Tetrahydrothiophene → Phenacyltetrahydrothiophenium bromide

HRID 1594447Notes

Reaction equation

HRID 1594447 reaction equation
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:4].[S:11]1[CH2:15][CH2:14][CH2:13][CH2:12]1>CC(C)=O>[Br-:1].[O:4]=[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH2:2][S+:11]1[CH2:15][CH2:14][CH2:13][CH2:12]1

Participants

4

Reactant 2

HCID 1127TetrahydrothiopheneHCID 6259Phenacyl bromide

Product 1

HCID 11346720Phenacyltetrahydrothiophenium bromide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

150 Parts of 2-bromoacetophenone was dissolved in 375 parts of acetone, and 66.5 parts of tetrahydrothiophene was added dropwise thereto. After the mixture was stirred at room temperature for 24 hours, white solid obtained was filtered, washed with acetone and then dried to obtain 207.9 parts of 1-(2-oxo-2-phenylethyl)tetrahydrothiophenium bromide in the form of white crystals.

Workup

  1. additionwas added dropwise
  2. customwhite solid obtained
  3. filtrationwas filtered
  4. washwashed with acetone
  5. customdried

Sources & evidence

ORD record
ord-427afa930feb4b0f94686649a729199f
Source dataset
uspto-grants-2007_11
Patent number
US07301047B2

Reaction notes

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