反应详情

(S)-1-Acetyl-2-methyl-4-benzylpiperazine (1.87 g) was hydrogenated over palladium hydroxide (600 mg) at ambient temperature for 3 hours. The catalyst was filtered off and the solvent was evaporated off. The residue was purified by column chromatography eluting with a mixture of methanol and chloroform (1:5) to give 440 mg of (S)-1-acetyl-2-methylpiperazine (440 mg).

1. filtrationThe catalyst was filtered off
2. customthe solvent was evaporated off
3. customThe residue was purified by column chromatography
4. washeluting with a mixture of methanol and chloroform (1:5)