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HRID1597946

反应详情

EQUATION

反应方程式

HRID 1597946 的结构方程式

REACTANTS

反应物

2
反应SMILES：COc1cc2ncnc(Cl)c2cc1OC
HCID2769364

4-Chloro-6,7-dimethoxyquinazoline

C10H9ClN2O2

反应SMILES：c1c2c(cc3c1OCO3)NCC2
HCID12369276

未命名化合物

PRODUCTS

产物

1
反应SMILES：COc1cc2ncnc(N3CCc4cc5c(cc43)OCO5)c2cc1OC
HCID18932776

未命名化合物

收率 93%

AUXILIARIES

试剂、催化剂与溶剂

1
反应SMILES：CC(C)O
溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

Utilizing a procedure analogous to that described in Example 1, this product was prepared in 93% yield from 6,7-dihydro-5H-[1,3]dioxolo[4,5-f]indole (1.1 eq.), and 4-chloro-6,7-dimethoxy-quinazoline (1.0 eq) in i-PrOH. (M.P. 225°-228° C. (dec); LC-MS: 352 (MH+); anal. RP18-HPLC RT: 3.91 min.).