反应详情

A 0.3 g quantity of 70% m-chloroperbenzoic acid was slowly added to 0.2 g of 3-(2,6-dichloro-4-trifluoromethylphenyl)-1-methyl-5-methylsulfenylpyrazole (compound 6) in 20 ml of anhydrous chloroform at room temperature with stirring, followed by further stirring overnight. The reaction mixture was poured into a 10% aqueous sodium sulfite solution, an organic layer was then separated off, washed with 5% aqueous sodium hydroxide solution and with brine and dried over anhydrous magnesium sulfate. The solvent was thereafter distilled off under reduced pressure, giving 0.3 g of the desired compound in the form of white crystals (quantitative crude yield).

1. stirringby further stirring overnight
2. customan organic layer was then separated off
3. washwashed with 5% aqueous sodium hydroxide solution and with brine
4. dry with materialdried over anhydrous magnesium sulfate
5. distillationThe solvent was thereafter distilled off under reduced pressure