Dimethylamine → HCID 19083693, compound

HRID 1598928Notes

Reaction equation

HRID 1598928 reaction equation
Br[O:2][CH2:3][CH:4]([O:24][O:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41])[CH2:5][O:6][O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23].[CH3:42][NH:43][CH3:44].C(OCC)(=O)C>C(Cl)(Cl)Cl.CCCCCC>[CH2:8]([O:7][O:6][CH2:5][CH:4]([CH2:3][O:2][N:43]([CH3:44])[CH3:42])[O:24][O:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]

Participants

6

Reactant 3

HCID 674DimethylamineHCID 8857Ethyl AcetateHCID 54034972HCID 54034972, compound

Product 1

HCID 19083693HCID 19083693, compound

Reagents, catalysts & solvents 2

HCID 6212ChloroformSolventHCID 8058HexaneSolvent

Procedure

900 mg of 3-bromo-1,2-dihexadecyloxy glycerol was dissolved in 30 ml chloroform in a 100 ml round bottom flask. 720 mg dimethylamine was added to yield an approximately 10 fold molar excess, and the reaction mixture stirred at room-temperature overnight. The progress of the reaction was measured by thin-layer-chromatography (30% ethyl acetate in hexane).

Workup

  1. customto yield an approximately 10 fold molar excess

Sources & evidence

ORD record
ord-46c610fd8e2d4ca1946f4ca4cd9a38b4
Source dataset
uspto-grants-1998_04
Patent number
US05739271

Reaction notes

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