Oxalyl chloride → HCID 19612334, compound
Reaction equation
[C:1]([O:5][O:6][C:7]([CH3:13])([CH3:12])[CH2:8][CH:9]([CH3:11])[OH:10])([CH3:4])([CH3:3])[CH3:2].[C:14](Cl)(=[O:18])[C:15]([Cl:17])=[O:16]>>[C:15]([Cl:17])(=[O:16])[C:14]([O:10][CH:9]([CH3:11])[CH2:8][C:7]([O:6][O:5][C:1]([CH3:4])([CH3:3])[CH3:2])([CH3:12])[CH3:13])=[O:18]Participants
3
Procedure
In this example the product was prepared in two synthetic steps. In the first step 3-t-butylperoxy-1,3-dimethylbutanol was reacted with 100% molar excess of oxalyl chloride. Upon completion of the reaction the excess oxalyl chloride was stripped from the product at reduced pressure to produce 3-t-butylperoxy-1,3-dimethylbutyl chlorooxalate having an assay of 98.1% and in a corrected yield of 98.4%. In the second step 3-t-butylperoxy-1,3-dimethylbutyl chlorooxalate was reacted with 3-hydroperoxy-1,3-dimethylbutanol in the presence of pyridine to yield the product as described below:
Sources & evidence
- ORD record
- ord-ca21bbbc0a1d4da092d68e954c088b3d
- Source dataset
- uspto-grants-1999_11
- Patent number
- US05981787
Reaction notes
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