反应详情

温度

60 °C

A mixture of tributylamine (0.5 ml, 2.1 mmol), palladium diacetate (0.03 g, 0.2 mmol), formic acid (0.06 ml, 1.3 mmol) and methyl 4-iodo-3-[2-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl]-1-propenyloxy]benzoate (0.65 g, 1.3 mmol) in acetonitrile (10 ml) is heated at 60° C. for 4 h. The reaction medium is concentrated on a rotary evaporator under vacuum at 40° C. 20 ml of water and 20 ml of ethyl ether are added. After separation of the phases by settling, the organic phase is washed twice with 20 ml of water, dried over magnesium sulphate and concentrated on a rotary evaporator under vacuum at 40° C.

1. concentrationThe reaction medium is concentrated on a rotary evaporator under vacuum at 40° C
2. addition20 ml of water and 20 ml of ethyl ether are added
3. customAfter separation of the phases
4. washthe organic phase is washed twice with 20 ml of water
5. dry with materialdried over magnesium sulphate
6. concentrationconcentrated on a rotary evaporator under vacuum at 40° C.