Methanol → HCID 15840106, compound

HRID 1602700Notes

Reaction equation

HRID 1602700 reaction equation
[CH3:1][C:2]1([C:15]2[CH:16]=[CH:17][C:18]3[O:22][C:21]4([CH3:29])[CH:23]5[CH2:27][C:26]([CH3:28])([C:20]4([CH3:30])[C:19]=3[CH:31]=2)[CH2:25][CH2:24]5)[C:6]2[CH:7]=[CH:8][C:9]([C:11]([O:13]C)=[O:12])=[CH:10][C:5]=2[O:4][CH2:3]1.[OH-].[Na+].[OH-].[Li+].CO>C1COCC1.O>[CH3:1][C:2]1([C:15]2[CH:16]=[CH:17][C:18]3[O:22][C:21]4([CH3:29])[CH:23]5[CH2:27][C:26]([CH3:28])([C:20]4([CH3:30])[C:19]=3[CH:31]=2)[CH2:25][CH2:24]5)[C:6]2[CH:7]=[CH:8][C:9]([C:11]([OH:13])=[O:12])=[CH:10][C:5]=2[O:4][CH2:3]1

Participants

7

Reactant 4

HCID 887MethanolHCID 3939Lithium HydroxideHCID 14798Sodium HydroxideHCID 15840105HCID 15840105, compound

Product 1

HCID 15840106HCID 15840106, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8028TetrahydrofuranSolvent

Procedure

A mixture of methyl 3-methyl-3-(1,2,3,4-tetrahydro-1,4a,9b-trimethyl-1,4-methanodibenzofur-8-yl)-2H-1-benzofuran-6-carboxylate (0.41 g, 0.98 mmol), sodium hydroxide (0.1 g, 2.5 mmol), lithium hydroxide (0.1 g, 2.5 mmol), methanol and water in THF is stirred for 48 h at room temperature.

Sources & evidence

ORD record
ord-dc06ae645f4946e88354aa1545e59a52
Source dataset
uspto-grants-1999_11
Patent number
US05981776

Reaction notes

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