Dichloromethane → HCID 15434936, compound

HRID 1604307Notes

Reaction equation

HRID 1604307 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:14](=[O:15])[NH:13][C:12](=O)[CH:11]=[N:10]2)[CH:5]=[C:6]([Cl:8])[CH:7]=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[Cl:36]CCl>>[Cl:36][C:12]1[CH:11]=[N:10][N:9]([C:4]2[CH:3]=[C:2]([Cl:1])[CH:7]=[C:6]([Cl:8])[CH:5]=2)[C:14](=[O:15])[N:13]=1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 11776TriphenylphosphineHCID 3662569HCID 3662569, compound

Product 1

HCID 15434936HCID 15434936, compound

Procedure

In 30 ml of dichloromethane suspended with 1.00 g of 2-(3,5-dichlorophenyl)-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione followed by addition of 2-fold morlar each of carbone tetrachloride and triphenylphosphine and refluxed for 12 hours. After the completion of the reaction, the resulted solution were purified by column chromatography (Merck Silica Gel 60 dichloromethane-carbontetrachloride=2:1). m.p. 148-149° C.

Workup

  1. temperaturerefluxed for 12 hours
  2. customAfter the completion of the reaction
  3. customthe resulted solution were purified by column chromatography (Merck Silica Gel 60 dichloromethane-carbontetrachloride=2:1)

Sources & evidence

ORD record
ord-82161c75c58d4dc7aef76b06dd9537bc
Source dataset
uspto-grants-1999_11
Patent number
US05994355

Reaction notes

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