Isopropanol → N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-4-(2-methoxyethylamino)-2-oxo-1-phenyl-1,2-dihydropyridine-3-carboxamide
Reaction equation
[CH3:1][O:2][CH2:3][CH2:4][NH2:5].[CH3:6][O:7][c:8]1[cH:9][c:10]2[c:11]([O:20][c:21]3[cH:22][cH:23][c:24]([NH:27][C:28](=[O:29])[c:30]4[c:31](=[O:43])[n:32](-[c:37]5[cH:38][cH:39][cH:40][cH:41][cH:42]5)[cH:33][cH:34][c:35]4[I:36])[n:25][cH:26]3)[cH:12][cH:13][n:14][c:15]2[cH:16][c:17]1[O:18][CH3:19].[CH:44]([OH:45])([CH3:46])[CH3:47].[Cl:48][CH2:49][Cl:50]>>[CH3:1][O:2][CH2:3][CH2:4][NH:5][c:35]1[c:30]([C:28]([NH:27][c:24]2[cH:23][cH:22][c:21]([O:20][c:11]3[c:10]4[cH:9][c:8]([O:7][CH3:6])[c:17]([O:18][CH3:19])[cH:16][c:15]4[n:14][cH:13][cH:12]3)[cH:26][n:25]2)=[O:29])[c:31](=[O:43])[n:32](-[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:33][cH:34]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-78cbe1dea5a0415a9e42dabe155ceeba
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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