Hydrochloric Acid → 7-Methylthio-3,7-dimethyloctan-1-al

HRID 1605132Notes

Reaction equation

HRID 1605132 reaction equation
C[O:2][CH:3](OC)[CH2:4][CH:5]([CH3:14])[CH2:6][CH2:7][CH2:8][C:9]([S:12][CH3:13])([CH3:11])[CH3:10].Cl>O1CCCC1>[CH3:13][S:12][C:9]([CH3:10])([CH3:11])[CH2:8][CH2:7][CH2:6][CH:5]([CH3:14])[CH2:4][CH:3]=[O:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 215493561,1-Dimethoxy-7-methylthio-3,7-dimethyloctane

Product 1

HCID 215493787-Methylthio-3,7-dimethyloctan-1-al

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A mixture of 5 g. of 1,1-dimethoxy-7-methylthio-3,7-dimethyloctane, 50 ml. of aqueous tetrahydrofuran (1:1) and 10 ml. of 3N hydrochloric acid is stirred at room temperature until hydrolysis is completed as followed by thin layer chromatography to give crude 7-metylthio-3,7-dimethyloctan-1-al which is worked up by extraction with ether and purified by chromatography.

Workup

  1. additionA mixture of 5 g

Sources & evidence

ORD record
ord-2295fa32d04b4e56a26d371013e0f380
Source dataset
uspto-grants-1976_04
Patent number
US03948996

Reaction notes

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