Hydroxide → 4-[3-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidine-1-carbonyl]oxypropanoyl]-1-(1-methylpiperidin-4-yl)piperazine-2-carboxylic acid
Reaction equation
[CH2:3]([CH3:4])[O:5][C:6](=[O:7])[CH:8]1[N:9]([CH:51]2[CH2:52][CH2:53][N:54]([CH3:57])[CH2:55][CH2:56]2)[CH2:10][CH2:11][N:12]([C:14]([CH:15]([CH2:16][c:17]2[cH:18][c:19]([Cl:28])[c:20]([NH2:27])[c:21]([C:23]([F:24])([F:25])[F:26])[cH:22]2)[O:29][C:30](=[O:31])[N:32]2[CH2:33][CH2:34][CH:35]([N:38]3[C:39](=[O:49])[NH:40][c:41]4[c:42]([cH:45][cH:46][cH:47][cH:48]4)[CH2:43][CH2:44]3)[CH2:36][CH2:37]2)=[O:50])[CH2:13]1.[CH2:58]1[O:59][CH2:60][CH2:61][CH2:62]1.[Li+:2].[OH-:1]>>[O:5]=[C:6]([OH:7])[CH:8]1[N:9]([CH:51]2[CH2:52][CH2:53][N:54]([CH3:57])[CH2:55][CH2:56]2)[CH2:10][CH2:11][N:12]([C:14]([CH:15]([CH2:16][c:17]2[cH:18][c:19]([Cl:28])[c:20]([NH2:27])[c:21]([C:23]([F:24])([F:25])[F:26])[cH:22]2)[O:29][C:30](=[O:31])[N:32]2[CH2:33][CH2:34][CH:35]([N:38]3[C:39](=[O:49])[NH:40][c:41]4[c:42]([cH:45][cH:46][cH:47][cH:48]4)[CH2:43][CH2:44]3)[CH2:36][CH2:37]2)=[O:50])[CH2:13]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-b4d45d4f3c52405f8bbf8b16a21ac12c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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