Triethylamine → HCID 20355088, compound

HRID 1606084Notes

Reaction equation

HRID 1606084 reaction equation
[CH2:1]([S:4][C:5]1[N:9]=[CH:8][NH:7][N:6]=1)[CH:2]=[CH2:3].SC1N=CNN=1.[CH2:16]([N:19]([CH2:23][CH:24]=[CH2:25])[C:20](Cl)=[O:21])[CH:17]=[CH2:18].C(N(CC)CC)C>O1CCCC1>[CH2:16]([N:19]([CH2:23][CH:24]=[CH2:25])[C:20]([N:7]1[CH:8]=[N:9][C:5]([S:4][CH2:1][CH:2]=[CH2:3])=[N:6]1)=[O:21])[CH:17]=[CH2:18]

Participants

6

Reactant 4

HCID 8471TriethylamineHCID 3449313Diallylcarbamyl chlorideHCID 178460804HCID 178460804, compoundHCID 178527894HCID 178527894, compound

Product 1

HCID 20355088HCID 20355088, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A mixture of 7.1 g. 3-allylthio-1,2,4-triazole, (m.p. 27° - 30°C., prepared from 3-mercapto-1,2,4-triazole in an analogous manner to that described in Example 1), 8.0 g. diallylcarbamoyl chloride, 7.5 ml. dry triethylamine and 100 ml. dry tetrahydrofuran was refluxed under anhydrous conditions for 48 hours. The reaction mixture was worked up as described in Example 1 to give 1-diallylcarbamoyl-3-allylthio-1,2,4-triazole, b.p. 120° - 122°C./0.1 mm. (95.2% 1-isomer by GLC assay).

Workup

  1. additionA mixture of 7.1 g

Sources & evidence

ORD record
ord-29902a0d7f45494eb5bdfb0e3b159d30
Source dataset
uspto-grants-1976_04
Patent number
US03952001

Reaction notes

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