Triethylamine → 1175-97-9

HRID 1606427Notes

Reaction equation

HRID 1606427 reaction equation
[CH3:1][C:2]1([CH3:24])[S:6][C@@H:5]2[C@H:7]([NH:10][C:11]([C@H:13]([NH2:20])[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[O:12])[C:8](=[O:9])[N:4]2[C@H:3]1[C:21]([OH:23])=[O:22].O.O.O.[CH2:28]([N:30]([CH2:33][CH3:34])[CH2:31][CH3:32])[CH3:29].S([O-])([O-])(=O)=O.[Mg+2]>ClCCl>[CH3:1][C:2]1([CH3:24])[S:6][C@@H:5]2[C@H:7]([NH:10][C:11]([C@H:13]([NH2:20])[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[O:12])[C:8](=[O:9])[N:4]2[C@H:3]1[C:21]([OH:23])=[O:22].[CH2:28]([N:30]([CH2:33][CH3:34])[CH2:31][CH3:32])[CH3:29]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 23565Ampicillin TrihydrateHCID 24083Sulfuric acid magnesium salt (1:1)

Product 1

HCID 129189941175-97-9

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

After stirring a mixture of 930 mg. of ampicillin trihydrate, 0.5 ml. of triethylamine, 700 mg. of magnesium sulfate, and 20 ml. of dichloromethane for one hour at room temperature, magnesium sulfate was filtered off to provide a dichloromethane solution of ampicillin triethylamine salt.

Workup

  1. additiona mixture of 930 mg
  2. filtrationmagnesium sulfate was filtered off

Sources & evidence

ORD record
ord-09494a144034436cb0db54f08efb7a68
Source dataset
uspto-grants-1976_04
Patent number
US03953428

Reaction notes

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