4-Methoxyphenylacetic Acid → 4-Methoxybenzaldehyde

HRID 1606468Notes

Reaction equation

HRID 1606468 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([OH:12])=O)=[CH:5][CH:4]=1.[NH2:13][C:14]([CH3:18])([CH3:17])[CH2:15][OH:16]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]([C:10]2[O:12][CH2:15][C:14]([CH3:18])([CH3:17])[N:13]=2)=[CH:9][C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[CH:7][CH:8]=1.[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH:9]=[O:16])=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 76904-Methoxyphenylacetic AcidHCID 118072-Amino-2-methyl-1-propanol

Product 2

HCID 312444-MethoxybenzaldehydeHCID 3041254HCID 3041254, compound

Procedure

2-[1,2-Bis(4-methoxyphenyl)ethenyl]-4,4-dimethyl-2-oxazoline (P-1728) was prepared by reacting 4-methoxyphenyl acetic acid with 2-amino-2-methyl-1-propanol and condensing the product thereby obtained with p-methoxybenzaldehyde. The boiling point was about 223 at 0.38 mm. The nmr spectrum was consistent with the proposed structure.

Sources & evidence

ORD record
ord-ca15ef2e458e4406851908855a591cc4
Source dataset
uspto-grants-1976_04
Patent number
US03953432

Reaction notes

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