Phenylacetyl chloride → HCID 178520253, compound

HRID 1606556Notes

Reaction equation

HRID 1606556 reaction equation
[NH:1]=[C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[SH:4](=[O:17])([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[NH:3]1.C(N(CC)CC)C.[C:25]1([CH2:31][C:32](Cl)=[O:33])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>C(Cl)(Cl)Cl>[C:25]1([CH2:31][C:32]([N:1]=[C:2]2[C:6]3[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=3[SH:4](=[O:17])([C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=3)[NH:3]2)=[O:33])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

5

Reactant 3

HCID 7679Phenylacetyl chlorideHCID 8471TriethylamineHCID 178509313HCID 178509313, compound

Product 1

HCID 178520253HCID 178520253, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

2.4 g. 3-imino-1-phenyl-3H-1,2-benzisothiazole-1-oxide are boiled for 1 hour with 1.32 g. triethylamine and 1.6 g. phenylacetyl chloride in 50 cc. chloroform. After working up in the usual manner, there is obtained 3-(phenylacetylimino)-1-phenyl-3H-1,2-benzisothiazole-1-oxide in the form of yellow crystals which, after recrystallisation from ethyl acetate, melt at 120°C.

Sources & evidence

ORD record
ord-6ea3e0e8ac6d4cb8b12e82cb088e3196
Source dataset
uspto-grants-1976_04
Patent number
US03953464

Reaction notes

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