N-methyl-2-pyrrolidone → HCID 86743338, compound

HRID 1606854Notes

Reaction equation

HRID 1606854 reaction equation
[CH3:1][NH:2][C:3]1[CH:8]=[C:7](F)[CH:6]=[C:5]([NH:10][CH3:11])[C:4]=1[N+:12]([O-:14])=[O:13].N[CH2:16][CH:17]([OH:20])[CH2:18][OH:19].C[N:22]1CCCC1=O>O1CCOCC1>[CH3:1][NH:2][C:3]1[C:8]([NH2:22])=[C:7]([CH2:16][CH:17]([OH:20])[CH2:18][OH:19])[CH:6]=[C:5]([NH:10][CH3:11])[C:4]=1[N+:12]([O-:14])=[O:13]

Participants

5

Reactant 3

HCID 13387N-methyl-2-pyrrolidoneHCID 735613-Amino-1,2-propanediolHCID 54495836HCID 54495836, compound

Product 1

HCID 86743338HCID 86743338, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A mixture of 0.01 mole (2 g) of 2-methylamino-6-methylamino-4-fluoronitrobenzene and 38 g of 3-amino propane 1,2-diol in 7 ml of dioxan diluted with 1 ml of N-methylpyrrolidone was refluxed for 15 hours.

Workup

  1. temperaturewas refluxed for 15 hours

Sources & evidence

ORD record
ord-13bb7e2dbacc47c4b10056615a302ce7
Source dataset
uspto-grants-1989_09
Patent number
US04863482

Reaction notes

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