Iodoethane → HCID 14184037, compound

HRID 1607639Notes

Reaction equation

HRID 1607639 reaction equation
[CH3:1][C:2](CC)=O.C(=O)([O-])[O-].[K+].[K+].C(I)C.[OH:15][C:16]1[CH:17]=[C:18]2[C:23](=[CH:24][C:25]=1[OH:26])[O:22][C:21]([CH3:28])([CH3:27])[CH2:20][C:19]2=[O:29]>>[OH:15][C:16]1[CH:17]=[C:18]2[C:23](=[CH:24][C:25]=1[O:26][CH2:1][CH3:2])[O:22][C:21]([CH3:27])([CH3:28])[CH2:20][C:19]2=[O:29]

Participants

5

Reactant 4

HCID 6340IodoethaneHCID 6569Methyl Ethyl KetoneHCID 11430Potassium CarbonateHCID 126377192,2-Dimethyl-6,7-dihydroxy-4-chromanone

Product 1

HCID 14184037HCID 14184037, compoundYield 85%

Procedure

In 100 ml of methyl-ethyl-ketone 4.2 g (20 millimoles) of 6,7-dihydroxy-2,2-dimethyl-4-chromanone are dissolved. To the solution 4.1 g (30 millimoles) of potassium carbonate and 4.7 g (2.4 ml, 30 millimoles) of ethyl iodide are added and the reaction mixture is heated to boiling for 3 hours. The reaction mixture is worked up according to Example 17. Thus 4.0 g of the title compound are obtained, yield 85%. Mp.: 129°-130° C.

Workup

  1. temperaturethe reaction mixture is heated

Sources & evidence

ORD record
ord-cb7c11fcbd02412bb39b6009a34fe513
Source dataset
uspto-grants-1989_09
Patent number
US04866089

Reaction notes

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