Hydrochloric Acid → HCID 11726065, compound

HRID 1607674Notes

Reaction equation

HRID 1607674 reaction equation
[CH3:1][C:2]1([C:7]2[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[C:9]([O:16][C:17]3[C:22]([Cl:23])=[CH:21][C:20]([Cl:24])=[CH:19][C:18]=3[Cl:25])[CH:8]=2)OCC[O:3]1.Cl>CC(C)=O>[N+:13]([C:10]1[CH:11]=[CH:12][C:7]([C:2](=[O:3])[CH3:1])=[CH:8][C:9]=1[O:16][C:17]1[C:18]([Cl:25])=[CH:19][C:20]([Cl:24])=[CH:21][C:22]=1[Cl:23])([O-:15])=[O:14]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 10319063HCID 10319063, compound

Product 1

HCID 11726065HCID 11726065, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 2-methyl-2-[4-nitro-3-(2,4,6-trichlorophenoxy)phenyl]-1,3-dioxolane (1.7 g) and 3N-hydrochloric acid (5 ml) in acetone (15 ml) was refluxed for 2 hours. The mixture was concentrated under reduced pressure. To the residue were added water and ethyl acetate. The organic layer was dried and concentrated to give a powder of 4'-nitro-3'-(2,4,6-trichlorophenoxy)acetophenone (1.5 g).

Workup

  1. temperaturewas refluxed for 2 hours
  2. concentrationThe mixture was concentrated under reduced pressure
  3. additionTo the residue were added water and ethyl acetate
  4. customThe organic layer was dried
  5. concentrationconcentrated

Sources & evidence

ORD record
ord-b4b8e7a3057f4bc0a10f5cd33dfded1d
Source dataset
uspto-grants-1989_09
Patent number
US04866091

Reaction notes

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