Ethanol → HCID 10000027, compound

HRID 1607689Notes

Reaction equation

HRID 1607689 reaction equation
[C:1]([C:4]1[CH:14]=[CH:13][C:7]([NH:8][S:9]([CH3:12])(=[O:11])=[O:10])=[C:6](SC2C=CC=CC=2C)[CH:5]=1)(=[O:3])[CH3:2].OO.[CH2:25]([OH:27])[CH3:26]>C(O)(=O)C>[C:1]([C:4]1[CH:14]=[CH:13][C:7]([NH:8][S:9]([CH3:12])(=[O:10])=[O:11])=[C:6]([O:27][C:25]2[CH:5]=[CH:4][CH:1]=[CH:2][C:26]=2[S:9]([CH3:12])(=[O:11])=[O:10])[CH:5]=1)(=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 702EthanolHCID 784Hydrogen PeroxideHCID 131716109HCID 131716109, compound

Product 1

HCID 10000027HCID 10000027, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
70 °C

Procedure

To a stirred solution of 4'-acetyl-2'-(2-methylthiophenoxy)methanesulfonanilide (1.2 g) in acetic acid (7 ml) was added dropwise 30% hydrogen peroxide (1 ml). The mixture was stirred for 2 hours at 70° C. and cooled to room temperature. Ethanol (10 ml) was added, and the precipitates were filtered and washed with ethanol to give colorless needles of 4'-acetyl-2'-(2-methylsulfonylphenoxy)methanesulfonanilide (1.1 g).

Workup

  1. temperaturecooled to room temperature
  2. filtrationthe precipitates were filtered
  3. washwashed with ethanol

Sources & evidence

ORD record
ord-5a8379ecc8814721aaadbb330e405dba
Source dataset
uspto-grants-1989_09
Patent number
US04866091

Reaction notes

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