Dimethylformamide → 2-Indan-2-yl-N-(6-oxo-2-phenyl-5,6-dihydro-1H-[1,2]diazepino[4,5,6-cd]indol-8-yl)-acetamide

HRID 160785Notes

Reaction equation

HRID 160785 reaction equation
[CH2:32]1[CH:33]([CH2:41][C:42](=[O:43])[OH:44])[CH2:34][c:35]2[cH:36][cH:37][cH:38][cH:39][c:40]21.[CH3:45][CH2:46][N:47]([CH2:48][CH3:49])[CH2:50][CH3:51].[CH3:79][N:80]([CH3:81])[CH:82]=[O:83].[Cl:76][CH2:77][Cl:78].[NH2:1][CH:2]([CH:3]1[CH2:4][CH2:26][CH2:27][CH2:28][CH2:29]1)[C:30]([NH:5][c:6]1[cH:7][c:8]2[c:9]3[c:10]([c:11](-[c:15]4[cH:16][cH:17][cH:18][cH:19][cH:20]4)[nH:12][c:13]3[cH:14]1)[cH:21][n:22][nH:23][c:24]2=[O:25])=[O:31].[P-:52]([F:53])([F:54])([F:55])([F:56])([F:57])[F:58].[n:59]1([O:60][C:61]([N:62]([CH3:63])[CH3:64])=[N+:65]([CH3:66])[CH3:67])[c:68]2[n:69][cH:70][cH:71][cH:72][c:73]2[n:74][n:75]1>>[NH:5]([c:6]1[cH:7][c:8]2[c:9]3[c:10]([c:11](-[c:15]4[cH:16][cH:17][cH:18][cH:19][cH:20]4)[nH:12][c:13]3[cH:14]1)[cH:21][n:22][nH:23][c:24]2=[O:25])[C:42]([CH2:41][CH:33]1[CH2:32][c:40]2[c:35]([cH:36][cH:37][cH:38][cH:39]2)[CH2:34]1)=[O:44]

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 8471TriethylamineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 51749552-(2,3-dihydro-1H-inden-2-yl)acetic AcidHCID 1354753612-amino-2-cyclohexyl-N-(9-oxo-2-phenyl-3,10,11-triazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13),11-pentaen-6-yl)acetamide

Product 1

HCID 1355072432-Indan-2-yl-N-(6-oxo-2-phenyl-5,6-dihydro-1H-[1,2]diazepino[4,5,6-cd]indol-8-yl)-acetamide

Sources & evidence

ORD record
ord-50575f28496544328e1d7effc32233ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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