Potassium Iodide → HCID 14181181, compound

HRID 1608047Notes

Reaction equation

HRID 1608047 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[CH2:7][CH2:6][CH2:5]2.Cl[CH2:14][C:15]([O:17][CH3:18])=[O:16].C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>CC(=O)CC>[O:12]=[C:8]1[CH2:7][CH2:6][CH2:5][C:4]2[CH:3]=[C:2]([O:1][CH2:14][C:15]([O:17][CH3:18])=[O:16])[CH:11]=[CH:10][C:9]1=2

Participants

6

Reactant 4

HCID 4875Potassium IodideHCID 7295Methyl chloroacetateHCID 11430Potassium CarbonateHCID 46794946-Hydroxy-3,4-dihydro-1(2H)-naphthalenone

Product 1

HCID 14181181HCID 14181181, compound

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

1 mol of 6-hydroxy-1-tetralone, 1.2 mols of methyl chloroacetate, 2 mols of potassium carbonate and 0.1 mol of potassium iodide are boiled under reflux in 2 1 of butanone for 6 hours. The mixture is filtered, the residue is rinsed with acetone and the filtrate is evaporated. The residue is taken up in methylene chloride, and the mixture is washed 3 times with 0.5 N NaOH solution, dried over sodium sulphate and evaporated.

Workup

  1. filtrationThe mixture is filtered
  2. washthe residue is rinsed with acetone
  3. customthe filtrate is evaporated
  4. washthe mixture is washed 3 times with 0.5 N NaOH solution
  5. dry with materialdried over sodium sulphate
  6. customevaporated

Sources & evidence

ORD record
ord-9d184557256242c9b3bd38778260260c
Source dataset
uspto-grants-1989_09
Patent number
US04868332

Reaction notes

Loading…