Methyl Thioglycolate → HCID 19848474, compound

HRID 1608120Notes

Reaction equation

HRID 1608120 reaction equation
[CH3:1][C:2]1([CH3:5])[CH2:4][NH:3]1.[SH:6][CH2:7][C:8]([O:10]C)=O>>[CH3:1][C:2]1([CH3:5])[NH:3][C:8](=[O:10])[CH2:7][S:6][CH2:4]1

Participants

3

Reactant 2

HCID 16907Methyl ThioglycolateHCID 2272442,2-Dimethylaziridine

Product 1

HCID 19848474HCID 19848474, compound

Procedure

2,2-Dimethylaziridine (35.5 g) was added dropwise with stirring at 100° C. to methyl mercaptoacetate (53 g) during 1.5 hours. After a further 2 hours at 100° C., the mixture was cooled and crystallized from ethyl acetate. Melting point: 151-152° C.

Workup

  1. temperaturethe mixture was cooled
  2. customcrystallized from ethyl acetate

Sources & evidence

ORD record
ord-36d5aa992e1f4219be0d63e4519d1ac2
Source dataset
uspto-grants-1989_09
Patent number
US04870063

Reaction notes

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