反应详情

A 3.25 g quantity (20 mmols) of 1-phenylpiperazine is dissolved in 10 ml of water, and a solution of 4.3 g (20 mmols) of sodium 2-bromoethanesulfonate in 10 ml of water is added dropwise thereto at room temperature with stirring. The mixture is subjected to reaction at room temperature for 1 hour and then at 70° C. overnight, and cooled. The crystals precipitated are collected by filtration and recrystallized from water-acetone.

1. customThe mixture is subjected to reaction at room temperature for 1 hour
2. temperatureat 70° C. overnight, and cooled
3. customThe crystals precipitated
4. filtrationare collected by filtration
5. customrecrystallized from water-acetone