Benzoylhydrazine → HCID 53808319, compound

HRID 1608179Notes

Reaction equation

HRID 1608179 reaction equation
[C:1]([NH:9][NH2:10])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][C:12]=1[CH:21]=O>C(O)C>[N:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][C:12]=1[CH:21]=[N:10][NH:9][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 11955BenzoylhydrazineHCID 796192-Quinolinecarboxaldehyde

Product 1

HCID 53808319HCID 53808319, compoundYield 50%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 4.08 gm (0.03 mole) of benzhydrazide, 4.72 gm (0.03 mole) of 2-quinolinecarboxaldehyde and 100 ml of absolute ethanol is refluxed 4 hr. The hot solution is filtered and cooled slowly to room temperature. The mixture is chilled. The crystals which separate are collected, washed with ether and dried to give 4.06 gm (50%) of the title compound having a melting point of 170.7° C.

Workup

  1. temperatureis refluxed 4 hr
  2. filtrationThe hot solution is filtered
  3. temperatureThe mixture is chilled
  4. customThe crystals which separate
  5. customare collected
  6. washwashed with ether
  7. customdried

Sources & evidence

ORD record
ord-20daf477a49f4711a728d4682696e8e7
Source dataset
uspto-grants-1989_09
Patent number
US04870082

Reaction notes

Loading…