Diethyl Carbonate → HCID 14745588, compound

HRID 1608455Notes

Reaction equation

HRID 1608455 reaction equation
[CH2:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[C:22](=O)([O:26]CC)[O:23][CH2:24][CH3:25].[O-]CC.[Na+]>C(O)C>[CH2:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([CH:16]([C:22]([O:23][CH2:24][CH3:25])=[O:26])[C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

5

Reactant 3

HCID 7766Diethyl CarbonateHCID 2723922Sodium ethoxideHCID 14745587HCID 14745587, compound

Product 1

HCID 14745588HCID 14745588, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

The obtained ethyl 4-n-octyloxyphenylacetate (79 g), ethanol (140 ml), diethyl carbonate (300 ml) and sodium ethoxide (19.3 g) are mixed, and the mixture is heated with stirring while ethanol is distilling off. The reaction mixture is transferred into ice water and is acidified with hydrochloric acid. The organic layer is separated and the solvent is distilled off to give diethyl 4-n-octyloxyphenylmalonate (91.6 g).

Workup

  1. temperaturethe mixture is heated
  2. distillationis distilling off
  3. customThe organic layer is separated
  4. distillationthe solvent is distilled off

Sources & evidence

ORD record
ord-a6118a15fe474bb1a607d8ea9e19e943
Source dataset
uspto-grants-1995_03
Patent number
US05395553

Reaction notes

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