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HRID1608571

反应详情

EQUATION

反应方程式

HRID 1608571 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：c1ccc(C(NC2C3CC4CC2CC(OCc2ccc(-c5nc6ccccc6o5)cc2)(C4)C3)(c2ccccc2)c2ccccc2)cc1
HCID15198019

未命名化合物

PRODUCTS

生成物

1
结构：Cl.NC1C2CC3CC1CC(OCc1ccc(-c4nc5ccccc5o4)cc1)(C3)C2
HCID67798427

未命名化合物

PROCEDURE

实验过程

A mixture of N-trityl-5-[4-(benzoxazol-2-yl)benzyloxy]tricyclo[3.3.1.13,7 ]decan-2-amine (200 mg) combined with ethanolic hydrogen chloride (5 ml) is stirred for an hour at room temperature. This is evaporated to dryness and the components separated via flash chromatography (eluting with 10% MeOH/CH2Cl2) to obtain 5-[4-(benzoxazol-2-yl)benzyloxy]tricyclo[3.3.1.13,7 ]-decan-2-amine hydrochloride (m.p. 278°-281° C.).

WORKUP

后处理

  1. customThis is evaporated to dryness
  2. customthe components separated via flash chromatography (eluting with 10% MeOH/CH2Cl2)