4-Methoxybenzyl alcohol → HCID 16687631, compound

HRID 1609170Notes

Reaction equation

HRID 1609170 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH2:7]O)=[CH:5][CH:4]=1.[F:11][Sb-:12]([F:17])([F:16])([F:15])([F:14])[F:13].[CH3:18][N:19]([CH3:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.S([O-])([O-])(=O)=O.[Mg+2]>[N+](C)([O-])=O>[F:11][Sb-:12]([F:17])([F:16])([F:15])([F:14])[F:13].[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH2:7][N+:19]([CH3:26])([CH3:18])[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 77384-Methoxybenzyl alcoholHCID 24083Sulfuric acid magnesium salt (1:1)HCID 86748579HCID 86748579, compound

Product 1

HCID 16687631HCID 16687631, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 6375NitromethaneSolvent

Procedure

13.81 g (0.1 mol) of 4-methoxybenzylalcohol and 35.78 g (0.1 mol) of N,N-dimethylaniline hexafluoroantimonate were dissolved in 100 g of nitromethane and, after the addition of 12.04 g (0.1 mol) of magnesium sulfate, allowed to react at 80° C. for 4 hours. After the completion of the reaction, the mixture was filtered and the filtrate was concentrated. The precipitated white solid was washed with ether and dried to give the titled compound. Yield: 70%.

Workup

  1. customto react at 80° C. for 4 hours
  2. customAfter the completion of the reaction
  3. filtrationthe mixture was filtered
  4. concentrationthe filtrate was concentrated
  5. washThe precipitated white solid was washed with ether
  6. customdried

Sources & evidence

ORD record
ord-3e7e6d96335b42d29b06efcdf2679a6d
Source dataset
uspto-grants-1995_03
Patent number
US05399695

Reaction notes

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