HCID 178526592, compound → HCID 178507514, compound

HRID 1609268Notes

Reaction equation

HRID 1609268 reaction equation
[N+:1]([C:4]1[CH:21]=[CH:20][CH:19]=[CH:18][C:5]=1[O:6][C:7]1[CH:8]=[C:9]([C:13]2[NH:17][N:16]=[N:15][N:14]=2)[CH:10]=[CH:11][CH:12]=1)([O-])=O>C(O)C.CN(C)C=O.[C].[Pd]>[NH:17]1[C:13]([C:9]2[CH:8]=[C:7]([CH:12]=[CH:11][CH:10]=2)[O:6][C:5]2[CH:18]=[CH:19][CH:20]=[CH:21][C:4]=2[NH2:1])=[N:14][N:15]=[N:16]1

Participants

5

Reactant 1

HCID 178526592HCID 178526592, compound

Product 1

HCID 178507514HCID 178507514, compoundYield 96.9%

Reagents, catalysts & solvents 3

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolventHCID 6228DimethylformamideSolvent

Procedure

In a mixture of 18 ml of ethanol and 9 ml of N,N-dimethylformamide was dissolved 1.5 g of 5-[3-(2-nitrophenoxy)phenyl]-1H-tetrazole and catalytic hydrogenation was carried out in the presence of 0.3 g of palladium-carbon at atmospheric temperature and pressure. After this reaction, the catalyst was filtered off and the filtrate was concentrated to give 1.3 g of the title compound as a colorless oil.

Workup

  1. customAfter this reaction
  2. filtrationthe catalyst was filtered off
  3. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-3cd4713068c648a68992414b5474dcf2
Source dataset
uspto-grants-1995_03
Patent number
US05399703

Reaction notes

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