反应详情

A mixture of 4.8 g of 4-chloromethyl-2-cyclobutyl-thiazole, 7.0 g of triphenylphosphine and 125 ml of toluene was heated to reflux for 16 hr and then cooled to room temperature. The mixture was then filtered to yield 4.8 g of [(2-cyclobutyl-4-thiazolyl)methyl]=triphenylphosphonium chloride.

1. temperaturewas heated
2. temperatureto reflux for 16 hr
3. filtrationThe mixture was then filtered