Succinic anhydride → HCID 20081050, compound

HRID 1609411Notes

Reaction equation

HRID 1609411 reaction equation
[C:1]1([CH2:7][S:8][S:9][CH2:10][CH2:11][OH:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:13]1(=[O:19])[O:18][C:16](=[O:17])[CH2:15][CH2:14]1>CN(C)C1C=CN=CC=1.O1CCCC1>[O:19]=[C:13]([O:12][CH2:11][CH2:10][S:9][S:8][CH2:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[CH2:14][CH2:15][C:16]([OH:18])=[O:17]

Participants

5

Reactant 2

HCID 7922Succinic anhydrideHCID 16075058HCID 16075058, compound

Product 1

HCID 20081050HCID 20081050, compound

Reagents, catalysts & solvents 2

HCID 142844-(Dimethylamino)pyridineCatalystHCID 8028TetrahydrofuranSolvent

Procedure

A mixture of 5-phenyl-3,4-dithiapentanol (832 mg, 4.15 mmol), succinic anhydride (415 mg, 4.15 mmol) and 4-dimethylaminopyridine (25 mg) in dry tetrahydrofuran (20 ml) was refluxed under nitrogen overnight. The mixture was then evaporated to dryness and used without further purification.

Workup

  1. temperaturewas refluxed under nitrogen overnight
  2. customThe mixture was then evaporated to dryness
  3. customused without further purification

Sources & evidence

ORD record
ord-f72eeefc47b84134a535bb9a96a69cf2
Source dataset
uspto-grants-1995_03
Patent number
US05401378

Reaction notes

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