Ammonia → HCID 22254637, compound

HRID 1611696Notes

Reaction equation

HRID 1611696 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1)#[N:2].[OH:10][C:11]1[CH:12]=[C:13]([CH:18]=[CH:19][CH:20]=1)[C:14](OC)=O.[NH3:21]>>[NH2:21][C:1]1[CH:3]=[CH:14][C:13]2[C:12](=[C:11]([O:10][CH:5]([CH3:4])[CH2:6][CH2:7][CH2:8][O:9][C:6]3[CH:7]=[CH:8][C:3]([C:1]#[N:2])=[CH:4][CH:5]=3)[CH:20]=[CH:19][CH:18]=2)[N:2]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 130194-CyanophenolHCID 88068Methyl 3-Hydroxybenzoate

Product 1

HCID 22254637HCID 22254637, compound

Procedure

The title compound was prepared according to the procedure described in Example 92 substituting 4-cyanophenol for methyl 3-hydroxybenzoate. 1H NMR (500 MHz, DMSO-d6) δ ppm 8.36 (d, 1H), 7.70 (m, 2H), 7.44 (m, 3H), 7.12 (d, 1H), 7.00 (m, 2H), 4.84 (m, 1H), 4.12 (m, 2H), 1.74–2.05 (m, 4H), 1.40 (d, 3H); MS (DCI/NH3) m/z 348 [M+H]+.

Sources & evidence

ORD record
ord-a7dc8867d625477ca06fed2daef4e3f7
Source dataset
uspto-grants-2006_01
Patent number
US06989392B2

Reaction notes

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