Dimethyl Sulfide → HCID 178439422, compound

HRID 1611847Notes

Reaction equation

HRID 1611847 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:11]=[C:12]([Cl:26])[C:13]=1[O:14][C:15]1[CH:20]=[CH:19][C:18]([O:21]C)=[C:17]([CH:23]([CH3:25])[CH3:24])[CH:16]=1)[CH2:5][C:6]1[NH:10][N:9]=[N:8][N:7]=1.B(F)(F)F.S(C)C>C(Cl)Cl>[Cl:1][C:2]1[CH:3]=[C:4]([CH:11]=[C:12]([Cl:26])[C:13]=1[O:14][C:15]1[CH:20]=[CH:19][C:18]([OH:21])=[C:17]([CH:23]([CH3:24])[CH3:25])[CH:16]=1)[CH2:5][C:6]1[NH:10][N:9]=[N:8][N:7]=1

Participants

5

Reactant 3

HCID 1068Dimethyl SulfideHCID 6356Boron trifluorideHCID 178492477HCID 178492477, compound

Product 1

HCID 178439422HCID 178439422, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A reaction mixture of 3,5-dichloro-4-(4-methoxy-3-isopropylphenoxy)-benzyltetrazole (60 mg), BF3.Me2S (0.5 ml) and CH2Cl2 (6 ml) was stirred at room temperature over night. The yield after purification was quantitative.

Workup

  1. customThe yield
  2. customafter purification

Sources & evidence

ORD record
ord-175e1c6b19ca4f27bb79ba5c0de4bb0f
Source dataset
uspto-grants-2006_01
Patent number
US06989402B1

Reaction notes

Loading…