Ethyl Acrylate → Ethyl 3-{N-[3-(pyrid-4-yl)propyl]-N-methyl-amino}-propionate

HRID 1612626Notes

Reaction equation

HRID 1612626 reaction equation
[C:1]([O:5][CH2:6][CH3:7])(=[O:4])[CH:2]=[CH2:3].[N:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH2:16][NH:17][CH3:18])=[CH:10][CH:9]=1>C(OCC)C>[N:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH2:16][N:17]([CH2:3][CH2:2][C:1]([O:5][CH2:6][CH3:7])=[O:4])[CH3:18])=[CH:10][CH:9]=1

Participants

4

Reactant 2

HCID 8821Ethyl AcrylateHCID 21974070N-Methyl-3-(pyridin-4-yl)propan-1-amine

Product 1

HCID 19776451Ethyl 3-{N-[3-(pyrid-4-yl)propyl]-N-methyl-amino}-propionate

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

15.1 g of ethyl acrylate are added portionwise to a solution of 22.5 g (0,15 Mol) of N-[3-(pyrid-4-yl)propyl]-N-methyl-amine in 50 ml of diethyl ether. The clear solution formed is allowed to stand overnight. The solvent is evaporated off. Ethyl 3-{N-[3-(pyrid-4-yl)propyl]-N-methyl-amino}-propionate is thus obtained as an oil.

Workup

  1. customThe clear solution formed
  2. customThe solvent is evaporated off

Sources & evidence

ORD record
ord-9d18e73defdc4860a3325a50d2b43f80
Source dataset
uspto-grants-1993_03
Patent number
US05190930

Reaction notes

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