1-Indanone → 1H-Indene-3-acetic acid

HRID 1613572Notes

Reaction equation

HRID 1613572 reaction equation
[C:1]1(=[CH:10][C:11]([O:13]CC)=[O:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.C1(=O)C2C(=CC=CC=2)CC1.P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>C1(C)C=CC=CC=1>[C:1]1([CH2:10][C:11]([OH:13])=[O:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH:2]=1

Participants

5

Reactant 3

HCID 67351-IndanoneHCID 11776TriphenylphosphineHCID 53401861Ethyl (2,3-dihydro-1H-inden-1-ylidene)acetate

Product 1

HCID 30140221H-Indene-3-acetic acidYield 90%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

2-(ind-1-en-1-yl)-acetic acid was prepared according to the method of H. Ahmed and N. Campbell J.C.S. (1960), 4115-4120, in a yield of 90%, from ethyl 2-(indan-1-ylidene)-acetate, which was itself prepared in a yield of 48% from indan-1-one and (C6H5)3P=CH--COOC2H5 in toluene.

Sources & evidence

ORD record
ord-9c587f65558c4875a69a3f7ec0361f3c
Source dataset
uspto-grants-1993_03
Patent number
US05194437

Reaction notes

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