Methane → HCID 19108679, compound

HRID 1613762Notes

Reaction equation

HRID 1613762 reaction equation
[S:1](Cl)(=[O:4])(=[O:3])[NH2:2].[Cl:6][C:7]1[CH:8]=[C:9]([CH:14]=[CH:15][C:16]=1[Cl:17])[O:10][CH2:11][CH2:12][OH:13].C>C(OC(C)C)(C)C>[S:1]([O:13][CH2:12][CH2:11][O:10][C:9]1[CH:14]=[CH:15][C:16]([Cl:17])=[C:7]([Cl:6])[CH:8]=1)(=[O:4])(=[O:3])[NH2:2]

Participants

5

Reactant 3

HCID 297MethaneHCID 24499Chlorosulfamic acidHCID 191086922-(3,4-Dichlorophenoxy)ethanol

Product 1

HCID 19108679HCID 19108679, compound

Reagents, catalysts & solvents 1

HCID 7914Diisopropyl EtherSolvent

Procedure

The title compound was prepared by the procedures of Example 33 from sulfamoyl chloride and to 2-(3,4-dichlorophenoxy)ethanol. The tan colored solid obtained was dissolved in isopropyl ether and the solution treated with charcoal and filtered through Celite®. The filtrate was evaporated under reduced pressure and the solid residue was recrystallized from isopropyl ether to give the title compound, mp 84°-85° C., in 19% yield.

Workup

  1. customThe tan colored solid obtained
  2. filtrationfiltered through Celite®
  3. customThe filtrate was evaporated under reduced pressure
  4. customthe solid residue was recrystallized from isopropyl ether

Sources & evidence

ORD record
ord-a16e58bd352b46c2b087164af903e422
Source dataset
uspto-grants-1993_03
Patent number
US05194446

Reaction notes

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