Phenol → HCID 14949203, compound

HRID 1613849Notes

Reaction equation

HRID 1613849 reaction equation
[CH3:1][Si:2]([CH3:15])([CH3:14])[N:3]=[S:4](Cl)([C:6]1[CH:11]=[CH:10][C:9]([F:12])=[CH:8][CH:7]=1)=[O:5].C(N(CC)CC)C.[C:23]1([OH:29])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>CC#N>[C:23]1([O:29][S:4]([C:6]2[CH:11]=[CH:10][C:9]([F:12])=[CH:8][CH:7]=2)(=[N:3][Si:2]([CH3:1])([CH3:14])[CH3:15])=[O:5])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

5

Reactant 3

HCID 996PhenolHCID 8471TriethylamineHCID 14949194HCID 14949194, compound

Product 1

HCID 14949203HCID 14949203, compoundYield 15%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The reactants used in the general procedure were sulfonimidoyl chloride (7c), triethylamine (0.0936 mol, 13.3 ml), phenol (0.0934 mol, 8.79 g). Boiling range of product: 125°-131° C./0.25 mm. Yield: 15%. 1H NMR signals (90 MHz, CH3CN): 0.24 (s, 9H), 6.83-7.57 (m, 7H), and 7.83-8.1 (m, 2H).

Workup

  1. custom125°-131° C./0.25 mm

Sources & evidence

ORD record
ord-4e07a3e6d6c349e7ada6c1a2b8c9d673
Source dataset
uspto-grants-1993_03
Patent number
US05194557

Reaction notes

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