Dimethylamine, hydrochloride → HCID 19773352, compound

HRID 1614256Notes

Reaction equation

HRID 1614256 reaction equation
[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][C:9](=O)[CH2:10]2)(=[O:3])[CH3:2].[ClH:16].[CH3:17][NH:18][CH3:19]>>[ClH:16].[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][CH:9]([N:18]([CH3:19])[CH3:17])[CH2:10]2)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 10473Dimethylamine, hydrochlorideHCID 148364565-Acetylamino-2-tetralone

Product 1

HCID 19773352HCID 19773352, compound

Procedure

Starting from 2.03 g (0.01 mol) of 5-acetylamino-2-tetralone and 2.45 g (0.03 mol) of dimethylaminehydrochloride the title compound is obtained analogously to Example 4.1.11 in a yield of 1.35 g (50.2% of theory) and with a melting point of 199° C. which does not change after recrystallisation from methanol/ether.

Sources & evidence

ORD record
ord-1cefde5815b94050a8cdb7d754e65348
Source dataset
uspto-grants-1993_03
Patent number
US05196454

Reaction notes

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