反应详情

To 5 ml of alcoholic hydrogen chloride 1 mmol of N-[4-(4-aminophenyl)butanoyl]thiazolidine was added and dissolved under heating. The mixture was stirred at room temperature for 2 hours. After the reaction, the solvent was evaporated under reduced pressure. To the residue was added anhydrous ether and precipitates thus produced were collected by filtration to obtain 0.28 g of colorless crystals of N-[4-(4-aminophenyl)butanoyl]thiazolidine hydrochloride (yield: 98%).

1. dissolutiondissolved
2. temperatureunder heating
3. customAfter the reaction
4. customthe solvent was evaporated under reduced pressure
5. additionTo the residue was added anhydrous ether
6. customprecipitates thus
7. customproduced
8. filtrationwere collected by filtration