Hydrochloric Acid → HCID 14822258, compound

HRID 1614562Notes

Reaction equation

HRID 1614562 reaction equation
[ClH:1].[NH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][CH2:11][C:12]([N:14]2[CH2:18][CH2:17][S:16][CH2:15]2)=[O:13])=[CH:5][CH:4]=1>>[ClH:1].[NH2:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:9][CH2:10][CH2:11][C:12]([N:14]2[CH2:18][CH2:17][S:16][CH2:15]2)=[O:13])=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 14822257N-[4-(4-aminophenyl)butanoyl]thiazolidine

Product 1

HCID 14822258HCID 14822258, compoundYield 98%

Procedure

To 5 ml of alcoholic hydrogen chloride 1 mmol of N-[4-(4-aminophenyl)butanoyl]thiazolidine was added and dissolved under heating. The mixture was stirred at room temperature for 2 hours. After the reaction, the solvent was evaporated under reduced pressure. To the residue was added anhydrous ether and precipitates thus produced were collected by filtration to obtain 0.28 g of colorless crystals of N-[4-(4-aminophenyl)butanoyl]thiazolidine hydrochloride (yield: 98%).

Workup

  1. dissolutiondissolved
  2. temperatureunder heating
  3. customAfter the reaction
  4. customthe solvent was evaporated under reduced pressure
  5. additionTo the residue was added anhydrous ether
  6. customprecipitates thus
  7. customproduced
  8. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-dd4eea7a48f64c49a0fdc4e86b926e08
Source dataset
uspto-grants-1993_03
Patent number
US05198450

Reaction notes

Loading…