Dichloromethane → tert-butyl (3RS,4RS)-4-(4-fluoro-phenyl)-3-(naphthalen-2-ylcarbonyloxy)-piperidine-1-carboxylate
Reaction equation
[CH2:42]([Cl:43])[Cl:44].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[CH3:45][N:46]([CH3:47])[c:48]1[cH:49][cH:50][n:51][cH:52][cH:53]1.[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([OH:21])[CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[cH:29]1[c:30]([C:39](=[O:40])[Cl:41])[cH:31][cH:32][c:33]2[cH:34][cH:35][cH:36][cH:37][c:38]12>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([O:21][C:39]([c:30]3[cH:29][c:38]4[c:33]([cH:32][cH:31]3)[cH:34][cH:35][cH:36][cH:37]4)=[O:40])[CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-dbf0bf9dacb747a89668524d14e9b42d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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