Hydroxyamine hydrochloride → HCID 136166869, compound

HRID 1617448Notes

Reaction equation

HRID 1617448 reaction equation
[C:1]1([CH:7]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH2:8][C:9]([C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[NH2:24][OH:25].C([O-])(O)=O.[Na+]>>[C:1]1([CH:7]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH2:8]/[C:9](/[C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)=[N:24]\[OH:25])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 443297Hydroxyamine hydrochlorideHCID 516892Sodium BicarbonateHCID 66668653HCID 66668653, compound

Product 1

HCID 136166869HCID 136166869, compound

Procedure

In analogy to example 1, step 2, from 3,3-diphenyl-1-pyridin-4-yl-propan-1-one and hydroxylamine hydrochloride in the presence of NaHCO3 was prepared the title compound as a white solid, MS (ESI+): m/z=303.1 ([M+H]+).

Sources & evidence

ORD record
ord-8e302e816cd4450d86058b899972b633
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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