HRID1617928

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID443297

未命名化合物

HCID516892

Sodium Bicarbonate

CHNaO3

结构：Cc1cc(Cl)ccc1C(CC(=O)c1ccc(=O)n(CCC(N)=O)c1)c1ccc(S(C)(=O)=O)cc1

HCID66666412

未命名化合物

PRODUCTS

生成物

$结构：Cc1cc(Cl)ccc1C(C/C(=N\O)c1ccc(=O)n(CCC(N)=O)c1)c1ccc(S(C)(=O)=O)cc1$

HCID58043329

未命名化合物

PROCEDURE

实验过程

In analogy to example 151, step 3, 3-(5-(3-(4-chloro-2-methylphenyl)-3-(4-(methylsulfonyl)phenyl)propanoyl)-2-oxopyridin-1(2H)-yl)propanamide was reacted with hydroxylamine hydrochloride in the presence of sodium hydrogencarbonate to give the title compound containing less than 10% of the corresponding Z isomer as an off-white solid, MS (ESI+): m/z=516.4 [M+H]+.