m-Chloroperbenzoic acid → HCID 70968088, compound

HRID 1618899Notes

Reaction equation

HRID 1618899 reaction equation
[CH3:1][C:2]1([CH3:23])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[O:11][C:12]2[C:13](=O)[NH:14][C:15]3[C:20]([CH:21]=2)=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:4][CH2:3]1.C1C=C(Cl)C=C(C(OO)=[O:32])C=1>C(Cl)(Cl)Cl>[CH3:1][C:2]1([CH3:23])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[O:11][C:12]2[CH:13]=[N+:14]([O-:32])[C:15]3[C:20]([CH:21]=2)=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:4][CH2:3]1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 86673627HCID 86673627, compound

Product 1

HCID 70968088HCID 70968088, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

0.2 g of 3-(1,1-dimethylindan-7-yloxy) quinolone was dissolved in 5 mL of chloroform, and 0.2 g of m-CPBA (70%) was added and stirred overnight at room temperature. After the reaction mixture was diluted with chloroform and washed with saturated sodium bicarbonate water, magnesium sulfate was added to dry the resultant. The solvent was evaporated under reduced pressure to obtain 0.2 g of 3-(1,1-dimethylindan-7-yloxy) quinoline-N-oxide.

Workup

  1. washwashed with saturated sodium bicarbonate water, magnesium sulfate
  2. additionwas added
  3. customto dry the resultant
  4. customThe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-0b943fd774d34f6d8313822c3fdef6c3
Source dataset
uspto-grants-2014_07
Patent number
US08772200B2

Reaction notes

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