反应详情

To a solution of 2-[(4-chloro-2-nitrophenyl)amino]benzoic acid (12.8 g, 43.7 mmol) in ethyl acetate (300 mL) was added platinum on sulfide coal 5%. The reaction mixture was hydrogenated at 2 bar for 5 h. After filtration through dicalite, washing with ethyl acetate and removal of the solvent under reduced pressure the title compound (11.8 g, 100%) was obtained.

1. filtrationAfter filtration through dicalite
2. washwashing with ethyl acetate and removal of the solvent under reduced pressure the title compound (11.8 g, 100%)
3. customwas obtained