Propargylamine → HCID 178456890, compound

HRID 1620477Notes

Reaction equation

HRID 1620477 reaction equation
S=[C:2]1[CH2:6][S:5][C:4](=[O:7])[NH:3]1.[CH2:8]([NH2:11])[C:9]#[CH:10]>C(O)C>[CH2:8]([NH:11][C:2]1[CH2:6][S:5][C:4](=[O:7])[N:3]=1)[C:9]#[CH:10]

Participants

4

Reactant 2

HCID 239041PropargylamineHCID 15395954-Sulfanylidene-1,3-thiazolidin-2-one

Product 1

HCID 178456890HCID 178456890, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a suspension of 4-thioxo-1,3-thiazolidin-2-one (12.8 g) in ethanol (200 mL) was added propargylamine (9.67 mL), and the mixture was stirred at room temperature overnight. The precipitate was collected by filtration, and washed with ethanol to give the title compound (11.9 g).

Workup

  1. filtrationThe precipitate was collected by filtration
  2. washwashed with ethanol

Sources & evidence

ORD record
ord-68a8c3d249cf4a34bd24cbf400be7778
Source dataset
uspto-grants-2014_07
Patent number
US08772277B2

Reaction notes

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