反应详情

To a solution of (R)-tert-butyl 4-ethynyl-2,2-dimethyloxazolidine-3-carboxylate (680 mg) (Tetrahedron 1996, 52, 11215.) in methanol (20 mL) was added trifluoroacetic acid (0.23 mL). The reaction mixture was stirred at room temperature for 4 hr and concentrated under reduced pressure to give the title compound (623 mg).

1. concentrationconcentrated under reduced pressure