Diglycolamine → HCID 178518155, compound

HRID 1620790Notes

Reaction equation

HRID 1620790 reaction equation
S=[C:2]1[CH2:6][S:5][C:4](=[O:7])[NH:3]1.[NH2:8][CH2:9][CH2:10][O:11][CH2:12][CH2:13][OH:14]>CC(O)C.C(OCC)(=O)C>[OH:14][CH2:13][CH2:12][O:11][CH2:10][CH2:9][NH:8][C:2]1[CH2:6][S:5][C:4](=[O:7])[N:3]=1

Participants

5

Reactant 2

HCID 13578DiglycolamineHCID 15395954-Sulfanylidene-1,3-thiazolidin-2-one

Product 1

HCID 178518155HCID 178518155, compound

Reagents, catalysts & solvents 2

HCID 3776IsopropanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

To a suspension of 4-thioxo-1,3-thiazolidin-2-one (10 g) in 2-propanol (25 mL) and ethyl acetate (75 mL) was added 2-(2-aminoethoxy)ethanol (7.50 mL), and the mixture was stirred at room temperature for 2 hr and further stirred for 2 hr under ice-cooling. The precipitate was collected by filtration, and the obtained solid was washed with ethyl acetate to give the title compound (12.5 g).

Workup

  1. stirringfurther stirred for 2 hr under ice-
  2. temperaturecooling
  3. filtrationThe precipitate was collected by filtration
  4. washthe obtained solid was washed with ethyl acetate

Sources & evidence

ORD record
ord-512b128c5f0e4e60bdddc71088e10353
Source dataset
uspto-grants-2014_07
Patent number
US08772277B2

Reaction notes

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