Tetrahydrofuran → 2-[1-(tert-Butyloxycarbonyl)pyrrolidin-2-yl]-3-(3-cyanophenyl)-propionic acid methyl ester
Reaction equation
[Br:28][CH2:29][c:30]1[cH:31][c:32]([C:33]#[N:34])[cH:35][cH:36][cH:37]1.[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[CH3:18][Si:19]([N-:20][Si:21]([CH3:22])([CH3:23])[CH3:24])([CH3:25])[CH3:26].[CH3:1][O:2][C:3]([CH2:4][CH:5]1[N:6]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:7][CH2:8][CH2:9]1)=[O:17].[Li+:27]>>[CH3:1][O:2][C:3]([CH:4]([CH:5]1[N:6]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:7][CH2:8][CH2:9]1)[CH2:29][c:30]1[cH:31][c:32]([C:33]#[N:34])[cH:35][cH:36][cH:37]1)=[O:17]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-565321bb85e449b6b82f04960a84dd55
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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