Potassium Cation → N-[3-(4-aminophenyl)propyl]-5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-amine

HRID 162138Notes

Reaction equation

HRID 162138 reaction equation
[C:29](=[O:30])([O-:31])[O-:32].[CH3:35][N:36]([CH3:37])[C:38](=[O:39])[CH3:40].[Cl:12][c:13]1[c:14]2[c:15]([n:16][cH:17][n:18]1)[s:19][cH:20][c:21]2-[c:22]1[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]1.[Cu:41][I:42].[K+:33].[K+:34].[NH2:1][CH2:2][CH2:3][CH2:4][c:5]1[cH:6][cH:7][c:8]([NH2:9])[cH:10][cH:11]1>>[NH:1]([CH2:2][CH2:3][CH2:4][c:5]1[cH:6][cH:7][c:8]([NH2:9])[cH:10][cH:11]1)[c:13]1[c:14]2[c:15]([n:16][cH:17][n:18]1)[s:19][cH:20][c:21]2-[c:22]1[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 31374DimethylacetamideHCID 27829114-Chloro-5-(4-fluorophenyl)thieno(2,3-d)pyrimidineHCID 216466834-(3-Aminopropyl)aniline

Product 1

HCID 57803008N-[3-(4-aminophenyl)propyl]-5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-d680253610344f668101de74920f4eb0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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